The introduction of COVID-19 therapies containing ritonavir has markedly expanded the scope of use for this medicine. As a strong cytochrome P450 3A4 inhibitor, the use of ritonavir is associated with ...

—A long-overdue study from Japan focused on the docetaxel-associated development of febrile neutropenia in cancer patients and its association with concomitant polypharmacy involving CYP3A4 inhibitors ...

A real-world study of the association between nivolumab exposure and efficacy in patients with metastatic melanoma. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract ...

Scientists explored selectively blocking the CYP3A4 protein responsible for breaking down large swaths of approved drugs, providing a way to improve drug efficacy. Scientists at St. Jude Children's ...

DOVER, Del., Dec. 9, 2024 /PRNewswire/ -- Lomond Therapeutics, a spin-out of Eilean Therapeutics LLC, a precision oncology-focused discovery and development platform, today announced results from ...

Codeine phosphate 30mg, acetaminophen 300mg; tabs; contains sulfites. Use lowest effective dose for shortest duration. Individualize. #3: initially 1–2 tabs every 4hrs as needed. #4: initially 1 tab ...