A world wide team of researchers addressed one of the trickiest drugs to prescribe -- the blood-thinner warfarin. Each patient's optimal dose varies widely, is hard to predict, and is crucial for his ...

In a large-scale study and an upcoming clinical trial, scientists supported by the National Institutes of Health address one of the trickiest issues in prescribing medicine—how to quickly optimize ...

A new report demonstrates that clinical and genetic factors affecting dose requirements for warfarin vary by race. The study proposes race-specific equations to help clinicians better calculate ...

Statins May Reduce VTE Risk Associated with Hormone Therapy Findings from a recent study suggests that clinical and genetic factors affecting warfarin dose requirements differ by race. Findings from a ...

HealthDay News — For warfarin-treated patients, carbamazepine co-treatment is associated with subtherapeutic anticoagulative effect and increased warfarin dose requirements, according to a study ...

Gene analysis failed in a U.S. clinical trial to help doctors select better doses of warfarin, the widely used blood-thinner, which can cause dangerous bleeding if doses are too high and fail to ...

The gene-guided dosing strategy of warfarin generally leads to over-dose in patients at doses lower than 2 mg/kg, and only 50% of individual variability in daily stable doses can be explained. In this ...

Feb. 24, 2003 — The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health stopped the Prevention of Recurrent Venous Thromboembolism (PREVENT) trial almost two years ...

Daily warfarin dosing requirements clearly decrease with advancing age. To examine the relation between age and warfarin dosing, researchers analyzed data from 101 U.S. sites that were participating ...

(WASHINGTON, May 29, 2015) - A new report demonstrates that clinical and genetic factors affecting dose requirements for warfarin vary by race. The study, published online today in Blood, the Journal ...