San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

Chicago Bears quarterback Caleb Williams' throws a dart to wide receiver DJ Moore for a 14-yard gain on fourth down against the Seattle Seahawks.

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

Less than a year ago, the 49ers and the Lions were the two best teams in the NFC. Now the Lions are on the verge of locking up the no. 1 seed.

Few, if any, NFL franchises can match the history, success, and overall talent of the San Francisco 49ers. Tied with the Dallas Cowboys for the third-most Super Bowl wins in NFL history with five, the ...

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

The San Francisco 49ers face slim odds of landing a top-nine pick in the 2025 NFL Draft. The Carolina Panthers and New York ...

NFL Week 17 matchups, odds, picks and props following Christmas Day games. Three Saturday contests followed by Sunday's most ...

Sling TV offers its Orange & Blue package of 48 channels at $55 per month that would serve your needs for locally available ...

San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

The Miami Dolphins inched closer to finishing their season with a winning record by beating the San Francisco 49ers a week ...

The Huskies and Tar Heels are tied with the 35th-ranked offense in the FBS, as they are both averaging 32.3 points per game.